Hemostatic agents prevent the blood loss and have the different site of action in complex coagulation and fibrinolysis pathways. Antifibrinolytic drugs inhibit the activation of plasminogen to plasmin preventing the lysis of fibrin and maintaining the clot stability. These Antifibrinolytic drugs prevent excessive bleeding. Tranexamic acid is used when the risk of hemorrhage is high because of increased fibrinolysis. Aprotinin, a proteolytic enzyme inhibitor which acts on plasmin and kallikrein. Antifibrinolytic drugs have nearly a ubiquitous use during important major surgeries when bleeding is expected most likely. The inhibition of fibrinolytic pathway after the tissue injury has constantly been showing a decrease in postoperative bleeding this ultimately results in the reduction in need of blood transfusion after an operation.
Global Antifibrinolytic Drugs Market: Dynamics
Growth in healthcare investments, the prevalence of angioedema and growing high-risk geriatric population, are the major factors driving the global market growth for angioedema treatment. In the next few years, the demand for angioedema treatment is expected to increase significantly in the economies such as China and Japan. Rising incidence of hereditary angioedema and high awareness about treatment and the management of angioedema together drive the global hereditary angioedema market.
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Global Antifibrinolytic Drugs Market: Segmentation
On the basis of Indications, the Global Antifibrinolytic Drugs market can be segmented into,
- Gynecology
- Menorrhagia
- Pregnancy
- Parturition
- Gynecological surgery
- Gastrointestinal (GI) bleeding
- Dental surgery
- Haemorrhage
- Bleeding disorders
- Hereditary angioedema
- Fibrinolytic response testing
- Surgeries
- Cardiac
- Orthopedic
- Liver
- Neurosurgery
On the basis of Drug Types, the Global Antifibrinolytic Drugs market can be segmented into,
- Amicar
- Aminocaproic acid
- Aprotinin
- Cyklokapron
- Fibrinogen, human
- Lysteda
- RiaSTAP
- Tranexamic acid injection
- Tranexamic acid oral
- Trasylol
On the basis of End User, the Global Antifibrinolytic Drugs market can be segmented into,
- Hospitals
- Ambulatory Surgical Centers
- Clinics
- Healthcare Specialty processes
- Others
On the basis of Region, the Global Antifibrinolytic Drugs market can be segmented into,
- North America
- Europe
- Asia Pacific
- Latin America
- Middle East & Africa
For treating menorrhagia, Tranexamic acid is widely used and is also recommended by the current National Institute for Health and Care Excellence guidelines. Tranexamic acid is effective in decreasing the blood loss by almost 40-50%. Etamsylate is used just occasionally to treat menorrhagia.
Global Antifibrinolytic Drugs Market: Region-wise Outlook
Geographically, North America is the dominating region in the Antifibrinolytic Drugs market owing to the advancing strict rules at the work place in this region, also due to a large number of aging population and broad technical applications of Antifibrinolytic Drugs in the region. Also, rising awareness of Antifibrinolytic Drugs has fueled the Antifibrinolytic Drugs market.The US holds the prominent market in the Antifibrinolytic Drugs market in North America trailed by Europe including Germany, France, and the UK. The Asian market for Antifibrinolytic Drugs is also expected to witness a high CAGR during the coming years. Increased foreign investments in this region will also boost the Antifibrinolytic Drugs market ahead. China and Japan are projected to be the fastest-growing in the Antifibrinolytic Drugs market.
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Global Antifibrinolytic Drugs Market: Key Players
Currently, the global Antifibrinolytic Drugs market is highly competitive owing to the involvement of many established players. Some of the key players in the global Antifibrinolytic Drugs market are Aurobindo Pharma Ltd, Acic Fine Chems, Akorn and Xanodyne Pharmaceuticals.