The cholesterol lowering biologic drugs offers a new, revolutionary alternative for people fighting with cholesterol with the same old treatments. The old method of treating cholesterol elevated levels includes a change in diet and consuming statin pills to prevent the body from making more bad cholesterol. The new class of PCSK-9 inhibitors is being approved by the FDA which works by helping the liver flush out the bad cholesterol instead of preventing the body from making low-density lipoproteins. The FDA has till now approved only two drugs Praluent and Repatha, both made from living things. The PCSK-9 is a protein which binds to the receptors, those which are responsible for getting the bad cholesterol out of the body.
Cholesterol Lowering Biologic Drugs Market: Drivers and Restraints
The cholesterol lowering biologics drug market is expected to boom owing to the number of population with high cholesterol levels, sedentary lifestyle and increasing research developments. According to the Indian Council of Medical Research, at least three-fourth of the country’s population has dyslipidemia, a condition where the individual has abnormal levels of triglycerides or cholesterol. The risk factors are obesity, hypertension poor lifestyle habits and diabetes. Moreover, the demand for biologics is driven by the dramatic shift in production technology and an expansion of targeted diseases.
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Cholesterol Lowering Biologic Drugs Market: Overview
There are two types of cholesterol, the good and the bad cholesterol. High-density lipoproteins also known as good cholesterol is responsible for carrying the bad kind to the liver from where it is removed. However, the low density lipoproteins buildup in the arteries which may block them eventually. This decreases or blocks the blood flow from reaching the brain and the heart leading to cases of stroke or heart disease.
The demand for cholesterol lowering biologics drugs is expected to boom with the added advantages it offers over statins. For instance, both Praluent and Repatha are to be taken every two weeks. The FDA, for now, has approved these two biologics drugs for a specific type of hereditary high cholesterol, but the increasing research developments will expand its application for wider high cholesterol audience. In January 2017, the U.S. Federal District court has decided to remove Praluent from the market. The company has been given a 30 days times to appeal the injunction and work towards a solution.
Cholesterol Lowering Biologic Drugs Market: Region-wise Outlook
In terms of geography, cholesterol lowering biologic drugs market has been divided into five regions including North- America, Europe, Asia- Pacific, Latin America and Middle-East & Africa. The population with high-level cholesterol and the presence of FDA-approved biologics is making North America region to dominate the cholesterol lowering biologic drugs market. CDC estimates more than 102 million American’s with high-level cholesterols compared to what’s considered healthy. Of that population of 102 million people, around 35 million have cholesterol levels high enough to put them at risk of heart disease.
Europe has already seen in few launches in biologics and will see more in coming years. The sales of biologics have overtaken the sales of traditional drugs as these therapies are targeted towards high-value therapies for the chronic condition.Asia-Pacific is the fastest growing region as the market of biosimilars across various players is growing at a high growth rate.
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Cholesterol Lowering Biologic Drugs Market: Key Market Participants
Few of the cholesterol lowering biologics drugs market participants are Amgen Inc., Regeneron Pharmaceuticals, Inc. and Alnylam Pharmaceuticals.