Anti-CD20 monoclonal antibodies are widely used in the treatment of B-cell malignancies. Anti-CD20 monoclonal antibodies are advantageous as they have enhanced killing activities and improves CD20 levels on the cell surface to increase the activity of lymphoma therapy. Since the inception of monoclonal antibodies, various type of potential mechanisms has been developed to increase the therapeutic efficiency of anti-CD20 monoclonal antibodies. This laid emphasis on developing next generation of anti-CD20 monoclonal antibodies to supplement additional potency in terms of functionality and efficacy. Anti-CD20 monoclonal antibodies work by targeting expressed CD20 marker on mature B cells and malignant B cells. This cascade of series works by complementing with the marker to deliver immunological attack from complement and FcR-expressing innate effectors (macrophages). This result in producing transmembrane signals by CD20 on engagement with anti-CD20 monoclonal antibodies, this favorable mechanism is utilized in malignant disease and autoimmune disorder treatment. Potential benefits from anti-CD20 monoclonal antibodies laid emphasis on developing next-generation anti-CD20 monoclonal antibodies and are currently in clinical trials.
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The market for anti-CD20 monoclonal antibodies is primarily driven by increasing research and development activities in generating potent anti-CD20 monoclonal antibodies. Various research funding and grants, and investment are done by both private and government bodies to support R&D activities and are driving the growth of anti-CD20 monoclonal antibodies market. In addition, rising demand for personalized medicine coupled with increasing use of immunotherapy, and potential benefits from the treatment in terms of fewer side effects, low cost of production are also impelling the market growth of anti-CD20 monoclonal antibodies. However, the high cost of production, the presence of alternative therapies such as chemotherapy and drugs, and stringent rules and regulations are the major obstacles to the growth of anti-CD20 monoclonal antibodies market.
The global anti-CD20 monoclonal antibodies market can be segmented on the basis of product type, end-user, and region.
- On the basis of product type, global anti-CD20 monoclonal antibodies market can be segmented as:
- First Generation Anti-CD20 Monoclonal Antibodies
- Second Generation Anti-CD20 Monoclonal Antibodies
- Third Generation Anti-CD20 Monoclonal Antibodies
- On the basis of end user, global anti-CD20 monoclonal antibodies market can be segmented as:
- Academic & Research Institutions
- Contract Research Organizations (CROs)
- On the basis of region, global anti-CD20 monoclonal antibodies market can be segmented as:
- North America
- Latin America
- Asia Pacific
- Middle East and Africa
The introduction of monoclonal antibodies has revolutionized targeted therapy for cancer. Since its introduction, various technological advancement has been made in generating a novel products such as next generation anti-CD20 monoclonal antibodies are humanized monoclonal antibodies, whereas first generation anti-CD20 monoclonal antibodies are chimeric monoclonal antibodies. In addition, some of the anti-CD20 monoclonal antibodies are enhanced to improve effector functions, including improvement in FcγR binding sites. The emergence of logistic services and e-commerce websites are also a vital component in boosting the growth of anti-CD20 monoclonal antibodies market.
Geographically, global anti-CD20 monoclonal antibodies market can be segmented into North America, Latin America, Europe, Asia-Pacific and Middle East & Africa. The market in North America is anticipated to show the largest market share for anti-CD20 monoclonal antibodies, followed by Europe, owing to the presence of sophisticated healthcare infrastructure. In addition, proper reimbursement of therapy procedure, and increasing awareness about personalized medicine among the general population are also gardening the market growth of anti-CD20 monoclonal antibodies. The market in Asia-Pacific region is estimated to grow at fastest CAGR over the forecast period owing to the presence of large population base, and increasing research and development activities supported by private and public bodies. However, the market in the Middle East & Africa shows the steady growth during the forecast period.
Some of the market participants in the global anti-CD20 monoclonal antibodies market are Biogen, Inc., Genentech, Inc. (F. Hoffmann-La Roche AG), Genmab A/S, Immunomedics, Inc., Novartis AG, Spectrum Pharmaceuticals, Inc., Bio-Rad Laboratories, Inc., and LFB Biotechnologies S.A.
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The report is a compilation of first-hand information, qualitative and quantitative assessment by industry analysts, inputs from industry experts and industry participants across the value chain. The report provides in-depth analysis of parent market trends, macroeconomic indicators and governing factors along with market attractiveness as per segments. The report also maps the qualitative impact of various market factors on market segments and geographies.