Chlorobutanol Market: Introduction
Chlorobutanol is a compound which is either colorless or white in color. Chlorobutanol has and odor and taste which is similar to that of camphor. The compound is an alcohol based preservative devoid of surfactant activity. The compound is similar to chloro hydrate as it is formed by the simple nucleophilic addition of chloroform and acetone. The concentration level of chlorobutanol which is made use of in various multi-ingredient formulations is 0.5%, which consequentially lends long-term stability to such products. However, chlorobutanol is known to retain anti-microbial activity in water at a concentration of 0.05%. The long terminal half-life of chlorobutanol, which is 37 days, limits its usage in sedatives as it results in accumulation within the human body if multiple doses are administered.
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Chlorobutanol finds widespread application in the eye-care market. Chlorobutanol also finds its application as a preservative in a number of pharmaceutical solutions, specifically in injectables. In addition, chlorobutanol is also used in a few oral sedatives and topical anesthetics. Further chlorobutanol is also used as a detergent preservative in eye drops and other ophthalmic therapeutic formulations. Other products which make use of chlorobutanol include mouth washs, salves, creams, ointments and cosmetics.
Chlorobutanol Market: Market Dynamics
The rapidly increasing geriatric population in addition to eye-related ailments in a number of people due to external causes such as rising pollution is contributing to the increase in production and sales of eye-care products which is as a consequence helping in the growth of the chlorobutanol market. The advent of generic drugs and the increase in the number of ophthalmic formulations are also aiding the growth of the chlorobutanol market. The primary reason for the migration of consumers to generic drugs for eye-disorders is the substantial cost savings which could be made.
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For instance, in order to promote the production of generic drugs, the FDA has been increasing its efforts to promote drug completion within branded and generic manufacturers to drive down costs and increase patient accessibility. In order to achieve this, the FDA is making the approval and market entry protocols and processes more efficient. This factor is contributing to the growth of the chlorobutanol market.
The chlorobutanol market is also facing challenges due to the decline in usage of the chemical. This has been attributed to the unstable nature of chlorobutanol when stored at room temperature for an extended period of time, however in the long run these challenges are expected to be outrun by the growing demand from healthcare sector.
Chlorobutanol Market: Regional Outlook
On the regional front, North America is the most dominant chlorobutanol market. This is due to the large number of pharmaceutical companies in the region. In addition, the rising geriatric population in the region which will increase the incidence of eye related disorders will drive the growth of the chlorobutanol market as one of the primary users of chlorobutanol is the eye care medication industry. Furthermore, Government funded medicare programmes which make medicines accessible to a wider population will also contribute significantly to the growth of the chlorobutanol market.
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Chlorobutanol Market: Key Market Participants
Some of the key market participants in the global chlorobutanol market are:
- Merck KGaA (formerly Sigma-Aldrich)
- Athenstaedt
- Laxachem Organics Pvt. Ltd.
- Spectrum Chemical Mfg. Corp.
- Toronto Research Chemicals
- Penta Manufacturing Company
- Bruchem, Inc.
- JSN Chemicals
- Capot Chemical Co. Ltd.
- Universal Preserve-A-Chem, Inc.
- Jigs Chemical
- Otto Chemie Pvt. Ltd.
- Polydrug Laboratories Pvt. Ltd.